| Sun, Mar 1 | vs Central Michigan Chippewas | W 7–5 | Jim Patterson Stadium |
| Tue, Mar 3 | vs Morehead State Eagles | L 5–13 | Louisville, KY |
| Fri, Mar 6 | vs Seton Hall Pirates | W 16–1 | Louisville, KY |
| Sat, Mar 7 | vsSeton Hall Pirates | W 13–3 | Louisville, KY |
| Sun, Mar 8 | vsSeton Hall Pirates | W 6–2 | Louisville, KY |
| Tue, Mar 10 | vs Marshall Thundering Herd | W 16–5 | Louisville, Ky. |
| Wed, Mar 11 | vsMarshall Thundering Herd | W 18–8 | Louisville, Ky. |
| Fri, Mar 13 | vs Notre Dame Fighting Irish | L 11–14 | Louisville, KY |
| Sat, Mar 14 | vsNotre Dame Fighting Irish | W 8–7 | Louisville, KY |
| Sun, Mar 15 | vsNotre Dame Fighting Irish | W 21–12 | Louisville, KY |
| Wed, Mar 18 | vs Northern Kentucky Norse | 8:00 PM | Louisville, Ky. |
| Sat, Mar 21 | @ North Carolina Tar Heels | L 0–0 | Boshamer Stadium |
| Sat, Mar 21 | @North Carolina Tar Heels | W 2–0 | Boshamer Stadium |
| Sun, Mar 22 | @North Carolina Tar Heels | L 6–7 | Boshamer Stadium |
| Tue, Mar 24 | @ Western Kentucky Hilltoppers | L 5–10 | Nick Denes Field |
| Fri, Mar 27 | vs Pittsburgh Panthers | L 3–4 | Louisville, KY |
| Sat, Mar 28 | vsPittsburgh Panthers | W 8–5 | Louisville, KY |
| Sun, Mar 29 | vsPittsburgh Panthers | L 7–13 | Louisville, KY |
| Tue, Mar 31 | @ Eastern Kentucky Colonels | W 17–7 | Lexington, Ky. |
