| Thu, Apr 2 | vsDuke (ACC) | 4:00 PM | — |
| Thu, Apr 2 | @ Duke Blue Devils | L 2-5 | Smith Family Stadium |
| Fri, Apr 3 | vsDuke (ACC) | 4:00 PM | — |
| Fri, Apr 3 | @Duke Blue Devils | L 3-4 | Smith Family Stadium |
| Sat, Apr 4 | vsDuke (ACC) | 4:00 PM | — |
| Sat, Apr 4 | @Duke Blue Devils | L 4-8 | Smith Family Stadium |
| Wed, Apr 8 | vs Louisiana Ragin' Cajuns | 4:00 PM | — |
| Wed, Apr 8 | vsLouisiana Ragin' Cajuns | W 5-4 | Palmer Park |
| Fri, Apr 10 | vsVirginia Tech (ACC) | 4:00 PM | — |
| Sat, Apr 11 | vsVirginia Tech (ACC) | 4:00 PM | — |
| Sun, Apr 12 | vsVirginia Tech (ACC) | 4:00 PM | — |
| Tue, Apr 21 | vs James Madison Dukes | 10:00 PM | Charlottesville, Va. |
| Fri, Apr 24 | vs NC State Wolfpack | 10:00 PM | Charlottesville, VA |
| Sat, Apr 25 | vsNC State Wolfpack | 6:00 PM | Charlottesville, VA |
| Sun, Apr 26 | vsNC State Wolfpack | 4:00 PM | Charlottesville, VA |
| Tue, Apr 28 | @ Liberty Flames | 9:00 PM | Kamphuis Field at Liberty Softball Stadium |
